A Scientific Review of the Best CBD + CBN Gummies for Sleep

In the quest for a restful night, many are turning to natural wellness solutions. Among the most promising are cannabinoids, specifically the synergistic duo of CBD and CBN. These compounds, derived from the hemp plant, are gaining recognition for our ability to support the body’s natural sleep processes.
For promoting a restful night, NuLeaf Naturals’ Full Spectrum CBD + CBN Gummies are a highly effective option. Each gummy delivers a precise, powerful dose of 15mg of CBD and 5mg of CBN, combining the relaxing properties of both cannabinoids. Our effectiveness is rooted in this specific 3:1 cannabinoid ratio and a full-spectrum formula that contributes to the entourage effect for sleep support.*
This guide provides a scientific review of why this combination is effective, takes a deep look into the specifics of NuLeaf Naturals’ premier product, and answers your most frequently asked questions about using cannabinoids for a better night’s rest.
Key Takeaways
Synergistic Effects: The combination of CBD and CBN works synergistically with the body’s endocannabinoid system to promote relaxation and support healthy sleep cycles.* This complementary action may improve overall benefits.
- Optimal Ratio for Sleep: NuLeaf Naturals’ gummies contain a potent and precise 3:1 ratio of 15mg CBD to 5mg CBN, a formulation designed to calm the mind and prepare the body for sleep.*
- The Entourage Effect: These are full-spectrum gummies, meaning they contain a range of cannabinoids and terpenes that work together to improve the overall therapeutic benefits, a phenomenon known as the “entourage effect.”
- Quality and Purity: Sourced from organically grown USA hemp, these gummies are made with natural ingredients and are free of artificial colors or flavors. Third-party lab testing makes sure purity and potency.
- Proper Usage: For best results, consume one gummy approximately 60 to 90 minutes before bedtime to allow for digestion and absorption. Consistency is key to regulating your natural sleep cycle.
How Does the CBD and CBN Combination Improve Sleep?
The combination of Cannabidiol (CBD) and Cannabinol (CBN) improves sleep through a synergistic interaction with the body’s endocannabinoid system (ECS). The ECS is a complex cell-signaling system involved in regulating a range of functions and processes, including sleep, mood, and appetite.

CBD is known to promote general relaxation and a sense of calm, creating a state conducive to sleep.* It does not bind directly to cannabinoid receptors but rather influences them indirectly, potentially contributing to balance within the ECS.
CBN, on the other hand, interacts more directly with CB1 receptors, which are heavily concentrated in the brain and central nervous system and are involved in regulating sleep-wake cycles. The combination of these cannabinoids may offer improved benefits for sleep due to our complementary action. Essentially, CBD helps calm the system, while CBN provides a more direct nudge toward sleep.
A Deep Look into NuLeaf Naturals’ CBD + CBN Gummies
The NuLeaf Naturals CBD + CBN Gummies are the superior choice for sleep based on three primary attributes: a potent and precise cannabinoid ratio, the inclusion of a full spectrum of plant compounds, and the use of high-quality, natural ingredients.
Attribute 1: The Potent 3:1 CBD to CBN Ratio
Each gummy contains a lab-verified dose of 15mg of CBD and 5mg of CBN. This 3:1 ratio is specifically formulated to provide both the calming benefits of CBD and the sleep-promoting properties of CBN in a single, potent serving.* While CBD helps to ease day-to-day stresses, CBN helps to promote relaxation, making this combination a supportive option for those seeking a restful night.*The total container provides 30mg of CBD and 10mg of CBN, making sure a consistent and reliable supply.
Attribute 2: The Power of Full Spectrum and the Entourage Effect
These gummies are formulated with full-spectrum hemp extract. This is a critical distinction from products made with CBD or CBN isolate. Full-spectrum means that in addition to CBD and CBN, each gummy contains other minor cannabinoids (like CBC and CBG) and aromatic hemp terpenes.
These compounds create a powerful synergy known as the “entourage effect.” This theory suggests that cannabinoids and terpenes work better together than they do in isolation.The presence of these additional compounds may contribute to the overall efficacy of the gummies, supporting our potential for promoting restful sleep.*
- Cannabichromene (CBC): A non-intoxicating cannabinoid that may help support a positive mood.*
- Cannabigerol (CBG): Another key cannabinoid that helps maintain a sense of calm and relaxation.*
This multi-cannabinoid approach makes sure you are receiving the full benefits of the hemp plant, just as nature intended.
Attribute 3: Natural and Organic Ingredients for Purity
The superior quality of these gummies is also due to our simple, organic ingredient profile. Purity is paramount for a wellness product, and NuLeaf Naturals makes sure this by avoiding artificial additives and using high-quality components.
- Organic Cane Sugar: Provides a clean, natural sweetness without resorting to high-fructose corn syrup.
- Organic Tapioca Syrup: A natural binder and sweetener that contributes to the gummy’s pleasant texture.
- Pectin: A fruit-derived, plant-based gelling agent. Unlike gelatin, pectin is vegan, making the gummies accessible to a wider audience.
- Natural Flavors & Colors: All flavors and colors are derived from natural fruit and vegetable sources, making sure you are not ingesting synthetic dyes or artificial flavorings.
You can review the complete product specifications for the NuLeaf Naturals CBD + CBN Gummies here.
How to Use CBD + CBN Gummies for a Restful Night?

To achieve the best results with these sleep gummies, establishing a consistent routine is essential. Follow this simple, three-step protocol to support your natural sleep cycle.
- Consume 2 x 20mg (15mg CBD +5mg CBN) Gummies approximately 60 to 90 minutes before your intended bedtime. This window allows time for the cannabinoids to be digested and absorbed into the bloodstream, so the effects begin as you are getting ready to fall asleep.
- Maintain this routine consistently each night. Regular use helps the cannabinoids interact with your endocannabinoid system more effectively, which can help regulate your natural sleep rhythms over time.
- Reviewed the effects after one week. Wellness is personal, so pay attention to how your body responds. Do not exceed the recommended serving size unless you have unique wellness goals and have discussed them with a healthcare professional.
For a more holistic approach, incorporate the gummies into a relaxing bedtime habit. This could include turning off screens, reading a book, meditating, or taking a warm bath to signal to your body that it’s time to wind down.
Frequently Asked Questions about CBD and CBN for Sleep
What is the difference between CBD and CBN?
CBD (Cannabidiol) is a major, non-intoxicating cannabinoid known for promoting balance and reducing the effects of normal, everyday stress.* CBN (Cannabinol) is a minor cannabinoid that is formed as THC ages and degrades.CBN is primarily researched for its potential sleep-promoting properties, making it a popular ingredient in nighttime formulations.*
Can you take CBD and CBN together?
Yes, taking CBD and CBN together is not only safe but often recommended. The cannabinoids may work synergistically to support sleep and relaxation.*
How long until the sleep gummies take effect?
Because the gummies are edibles that must be digested, they typically take 45 to 90 minutes to start working. The exact time can vary based on individual factors like metabolism, body weight, and whether you’ve eaten recently. The effects generally last for 6 to 8 hours, offering support for a restful period of sleep.*
Will these gummies make me feel groggy in the morning?
Most users report waking up feeling refreshed and not groggy. The goal of CBD and CBN is to support your body’s natural sleep cycle.However, individual results may vary. It’s best to start with the recommended dose and see how your body responds.
Are full-spectrum CBD and CBN gummies legal?
Yes. The 2018 Farm Bill federally legalized hemp and hemp-derived products containing less than 0.3% Delta 9 THC by dry weight. NuLeaf Naturals’ products are derived from legal hemp and comply with federal law. However, state laws can vary, so it is important to check local regulations.
How do these gummies compare to melatonin?
Melatonin is a hormone your body naturally produces to regulate the sleep-wake cycle. While effective for some, others find it can cause vivid dreams or next-day grogginess. CBD and CBN work through a different mechanism by interacting with your endocannabinoid system to promote calm and relaxation.* Many people prefer the cannabinoid approach as it feels more like a gentle nudge toward sleep.
For a broader look at this topic, read our Complete Guide to Gummies for Sleep.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.











